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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Ependymoma

Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site📍 Boadilla del Monte Fundación de investigación HM · Tests: Olaparib; 177Lu-DOTATATE Natural History Study of Patients With Neurofibromatosis Type 2 NCT00598351n/a1 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents NCT05151718n/a1 site📍 Toulouse Institut Claudius Regaud ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors NCT04732065Phase 17 sites📍 San Francisco📍 Washington D.C.📍 Atlanta Sabine Mueller, MD, PhD · Tests: ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS) NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors NCT07664176Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: NeuroNavigation-Guided Focused Ultrasound (NgFUS), Lumason, Nivolumab International HIT-MED Registry (I-HIT-MED) NCT02417324n/a57 sites📍 Aachen📍 Augsburg📍 Berlin Universitätsklinikum Hamburg-Eppendorf Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification NCT05259605n/a42 sites📍 Innsbruck📍 Vienna📍 Aalst European Organisation for Research and Treatment of Cancer … · Tests: Observational Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors NCT04185038Phase 11 site📍 Seattle Seattle Children's Hospital · Tests: SCRI-CARB7H3(s); B7H3-specific chimeric antigen receptor (CAR) T cel Multicenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors NCT07056023n/a1 site📍 Münster University Hospital Muenster Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling NCT05857969Phase 11 site📍 Miami Florida International University · Tests: Functional Precision Medicine Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) NCT04374305Phase 26 sites📍 Los Angeles📍 Miami📍 Indianopolis Scott R. Plotkin, MD, PhD · Tests: Brigatinib, Neratinib, Retifanlimab, Bevacizumab A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. NCT07017816EARLY Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: SGT-53, hypofractionated radiotherapy with immunotherapy, Nivolumab Determine Maximum Tolerated Dose, Safety, and Tolerability of Rhenium (186Re) in Pediatric Recurrent, Refractory or Progressive Ependymoma and High-Grade Glioma NCT07061626Phase 11 site📍 Chicago Cerenome · Tests: Rhenium-186 Nanoliposome HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites📍 Birmingham📍 St Louis📍 Houston M.D. Anderson Cancer Center · Tests: G207 Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma NCT07226453Phase 212 sites📍 Birmingham📍 San Francisco📍 Washington D.C. University of California, San Francisco · Tests: Metformin, Planned Surgical Resection, Magnetic Resonance Imaging (MRI), Specimen Collection, MR spectroscopy (MRS) Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer NCT05106296Phase 11 site📍 Augusta Theodore S. Johnson · Tests: Indoximod, Ibrutinib, Cyclophosphamide, Etoposide, Ibrutinib Systemic Biomarkers to Predict Radiation-Induced Neurocognitive Decline NCT06779487n/a1 site📍 Mumbai Tata Memorial Centre MRE Evaluation for Spinal Cord Tumor Surgery: Stiffness and Adhesion Assessment NCT05957679NA1 site📍 Shenyang Shengjing Hospital · Tests: Magnetic Resonance Elastography, Assessment and Recording Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) NCT06193759Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: Multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized… LET Optimized IMPT in Treating Pediatric Patients With Ependymoma NCT03750513Phase 12 sites📍 Boston📍 Houston M.D. Anderson Cancer Center · Tests: Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy, Quality-of-Life Assessment, Questionnaire Administ… Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China NCT05672043n/a1 site📍 Beijing Beijing Tiantan Hospital Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors NCT01356290Phase 222 sites📍 Chicago📍 Boston📍 Grand Rapids Medical University of Vienna · Tests: Bevacizumab, Thalidomide, Celecoxib, Fenofibric acid, Etoposide B7-H3.CD28Z.CART in CNS Neoplasms NCT07390539Phase 12 sites📍 Boston📍 Boston Robbie Majzner · Tests: B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma NCT05057702NA9 sites📍 Los Angeles📍 San Diego📍 San Francisco University of California, San Francisco · Tests: Specialized Tumor Board Treatment Plan, Combinations Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors NCT07424092Phase 22 sites📍 Utrecht📍 Pamplona Clinica Universidad de Navarra, Universidad de Navarra · Tests: DNX-2401 An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma NCT02265770Phase 2, Phase 340 sites📍 Graz📍 Liège📍 Brno Centre Leon Berard · Tests: 16 weeks of VEC + CDDP, VEC + HD-MTX, Chemotherapy + Valproate, Conformal radiotherapy, VEC Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms NCT04541082Phase 11 site📍 Bethesda Jazz Pharmaceuticals · Tests: ONC206 Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors NCT05278208Phase 1, Phase 24 sites📍 Aurora📍 Cincinnati📍 Columbus Nationwide Children's Hospital · Tests: LUTATHERA® (Lutetium Lu 177 dotatate) PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications NCT06161519Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: PLX038 Pharmacoscopy for Patients With Refractory Primary Brain Tumors NCT06804655Phase 23 sites📍 Basel📍 Sankt Gallen📍 Zurich University of Zurich · Tests: Pharmacoscopy 1.0
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