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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for HFrEF - Heart Failure With Reduced Ejection Fraction

Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study NCT06516562n/a1 site๐Ÿ“ Ho Chi Minh City University Medical Center Ho Chi Minh City (UMC) ยท Tests: Optimal treatment Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: Conduction system pacing, Right ventricular apical pacing Empagliflozin in Heart Failure with Reduced Ejection Fraction and End Stage Renal Disease NCT06249932Phase 42 sites๐Ÿ“ Hsinchu๐Ÿ“ Taipei National Taiwan University Hospital ยท Tests: Empagliflozin 25 MG, Placebo Eccentric Muscle Training in Cardiac Rehabilitation NCT07636343NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: eccentric bike training, eccentric overload training, aerobic treadmill training, aerobic bike training, traditional dyโ€ฆ Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score NCT07490067Phase 41 site๐Ÿ“ Ann Arbor University of Michigan ยท Tests: Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogenoโ€ฆ Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction NCT05828719NA1 site๐Ÿ“ Seoul Samsung Medical Center ยท Tests: Percutaneous coronary intervention Predictive Factors of Response to Phase II Cardiac Rehabilitation in Heart Failure With Reduced Ejection Fraction NCT07164911n/a1 site๐Ÿ“ Corbie Centre Hospitalier de Corbie The CardioClip Study NCT06241430NA1 site๐Ÿ“ New York Columbia University ยท Tests: CardioMEMS SHengXIaN-QuYu DEcoction in Heart Failure With Reduced and Mildly Reduced Ejection Fraction NCT05583773Phase 426 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing China-Japan Friendship Hospital ยท Tests: ShengXian-QuYu Decoction, Placebo Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF NCT07347925n/a1 site๐Ÿ“ Al Mansurah Future University in Egypt ยท Tests: Prehospital ARNI use, No prehospital ARNI use Lumacaftor Yields Reversal of Impaired Cerebral Blood Flow in Heart Failure Patients NCT07695090Phase 22 sites๐Ÿ“ Toronto๐Ÿ“ Toronto Qanatpharma AG ยท Tests: Lumacaftor 200 MG, Placebo A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease NCT07214376NA18 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Weston Pulnovo Medical, Inc. ยท Tests: Pulmonary Artery Denervation (PADN), Sham procedure control The FOCUS-ADHF Registry NCT06726109n/a4 sites๐Ÿ“ Genk๐Ÿ“ Rivoli๐Ÿ“ Turin ASL Cittร  di Torino Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure NCT03480633n/a1 site๐Ÿ“ Boston Massachusetts General Hospital Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure NCT06342492n/a1 site๐Ÿ“ Overland Park Kansas City Heart Rhythm Research Foundation ยท Tests: Coronary Sinus Lead Revision Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure NCT06552637NA5 sites๐Ÿ“ Indianapolis๐Ÿ“ Tulsa๐Ÿ“ Philadelphia VisCardia Inc. ยท Tests: Synchronized Diaphragmatic Stimulation Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF NCT06078436NA1 site๐Ÿ“ Seoul Min-Seok Kim ยท Tests: Pulmonary artery catheter Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy NCT06128980Phase 2, Phase 31 site๐Ÿ“ Copenhagen Herlev and Gentofte Hospital ยท Tests: GDMT Ketones, SGLT2, HFrEF NCT06229678EARLY Phase 11 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Empagliflozin 25 MG Oral Tablet, Placebo, Acipimox 250 Mg Oral Capsule Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Ketone Monoester (KE) AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices NCT06909682n/a1 site๐Ÿ“ Salerno University of Salerno ยท Tests: Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up BAROSTIM THERAPYโ„ข in Heart Failure With Reduced Ejection Fraction NCT02880618n/a30 sites๐Ÿ“ Hamburg๐Ÿ“ Bad Oeynhausen๐Ÿ“ Berlin CVRx, Inc. ยท Tests: Barostim Neoโ„ข System Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator NCT06964464Phase 413 sites๐Ÿ“ Scottsdale๐Ÿ“ Rome๐Ÿ“ Shawnee Mission University of Rochester ยท Tests: Metoprolol Succinate, Carvedilol Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction NCT07118410NA1 site๐Ÿ“ Nรฎmes Centre Hospitalier Universitaire de Nฤซmes ยท Tests: Application of a vascular restriction device during resistance training Exercise Rehabilitation for Cardiorenal Syndrome in HFrEF Patients NCT07167368NA1 site๐Ÿ“ Nantong Haiyan Pan ยท Tests: Standardized Basic Drug Therapy for HFrEF with Chronic Kidney Dysfunction, Home-based Personalized Exercise Rehabilitatโ€ฆ Swedish Cardiac And Renal Failure Study-1 NCT07029503Phase 21 site๐Ÿ“ Stockholm Karolinska Institutet ยท Tests: Eplerenone Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction NCT07644806NA1 site๐Ÿ“ Norfolk Old Dominion University ยท Tests: Extra-virgin olive oil CHF-COV Reduced (Chronic Heart Failure With Reduced Ejection Fraction - COngestion eValuation) NCT05089162NA1 site๐Ÿ“ Vandล“uvre-lรจs-Nancy Pr. Nicolas GIRERD ยท Tests: Clinical examination centered on congestion, Cardiac, pulmonary, peritoneal, jugular and renal Doppler ultrasounds, Bloโ€ฆ An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting NCT06148935n/a1 site๐Ÿ“ Multiple Locations Bayer ยท Tests: Vericiguat (Verquvo, BAY1021189) HFrEF Polypill in Sri Lanka RCT NCT07569640Phase 312 sites๐Ÿ“ Kandy๐Ÿ“ Anuradhapura๐Ÿ“ Kurunegala Washington University School of Medicine ยท Tests: Usual Care, HFrEF Polypill
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