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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure and Preserved Ejection Fraction

Rifaximin and Cardiac Function in Patients with Heart Failure with Preserved Ejection Fraction NCT06652087NA1 site📍 Moscow I.M. Sechenov First Moscow State Medical University · Tests: Rifaximin, Standard HFpEF treatment Multimodality Imaging in the Screening, Diagnosis and Risk StratifictiON of HFpEF NCT04603404n/a1 site📍 Beijing Chinese Academy of Medical Sciences, Fuwai Hospital Electroporation Treatment for Early AF Management in Heart Failure With Preserved Ejection Fraction (HFpEF) Pilot Study NCT07385417NA1 site📍 Frankfurt am Main Cardioangiologisches Centrum Bethanien · Tests: AF Ablation CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation NCT06762964Phase 21 site📍 Rochester Mayo Clinic · Tests: Dapagliflozin tablet, Placebo Tablet Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site📍 Edegem University Hospital, Antwerp · Tests: Conduction system pacing, Right ventricular apical pacing Tailored Exercise Training Study Among Adults With HFpEF NCT07223242Phase 2, Phase 31 site📍 Dallas University of Texas Southwestern Medical Center · Tests: Moderate-intensity continuous training (MCT), Resistance training, Weight loss A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity NCT07567001Phase 3838 sites📍 Alexander City📍 Birmingham📍 Fairhope Novo Nordisk A/S · Tests: NNC0487-0111, Placebo OBESE-HFpEF: Towards Preventing Obesity Related HFpEF NCT07539766n/a1 site📍 Heerlen Zuyderland Medisch Centrum Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity NCT07037459Phase 3657 sites📍 Birmingham📍 Dothan📍 Fairhope Amgen · Tests: Maridebart cafraglutide, Placebo Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction NCT07634640EARLY Phase 11 site📍 Gainesville University of Florida · Tests: Ferumoxytol infusion The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction NCT06768437n/a1 site📍 Leicester University of Leicester Left Bundle Branch Pacing vs Right Ventricular Pacing on AHRE Burden in Patients With Preserved LVEF NCT07250529NA1 site📍 Pátrai University Hospital of Patras · Tests: Right Ventricular Pacing, Left Bundle Branch Pacing HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction NCT05784753NA3 sites📍 Detroit📍 Omaha📍 Charlottesville University of Nebraska · Tests: HEART Camp, HEART Camp Connect SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial NCT05138575Phase 21 site📍 Philadelphia University of Pennsylvania · Tests: Empagliflozin + Potassium Chloride, Empagliflozin + Potassium Nitrate, Potassium Chloride + Placebo for Empagliflozin PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF NCT07324772NA1 site📍 Chicago Northwestern University · Tests: progressive resistance training, combined aerobic + resistance training The Prognostic Role and Diagnostic Efficacy of Exercise Right Heart Catheterization With a Simultaneous Echocardiography in Patients With Dyspnea on Exertion NCT05490901n/a1 site📍 Seoul Samsung Medical Center · Tests: Exercise hemodynamic test Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction NCT07560436Phase 21 site📍 London King's College London · Tests: Percutaneous coronary intervention, Placebo procedure A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease NCT07214376NA18 sites📍 Tucson📍 New Haven📍 Weston Pulnovo Medical, Inc. · Tests: Pulmonary Artery Denervation (PADN), Sham procedure control Novel Approaches for Improving Vascular Function in Veterans With HFpEF NCT06312748Phase 11 site📍 Salt Lake City VA Office of Research and Development · Tests: L-Citrulline, Placebo for L-Citrulline, BH4, Placebo for BH4, Atorvastatin Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure NCT03480633n/a1 site📍 Boston Massachusetts General Hospital Accelerated Pacing and Cardiac Filling Pressures During Exercise in Patients With Heart Failure With Preserved Ejection Fraction NCT07270536NA2 sites📍 Hasselt📍 Leuven Universitaire Ziekenhuizen KU Leuven · Tests: Accelerated pacing with AV-delay optimization during rest and light intensity cycling AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices NCT06909682n/a1 site📍 Salerno University of Salerno · Tests: Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up Study to Collect High-Resolution ECG Data and Patient Insights on Heart Failure Care NCT06809686n/a2 sites📍 London📍 London Richmond Research Institute A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) NCT06991257Phase 2150 sites📍 Beverly Hills📍 Lake Forest📍 Santa Maria Pfizer · Tests: Placebo, Low Dose PF-07328948, Medium Dose PF-07328948, High Dose PF-07328948 Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF NCT06208007n/a1 site📍 Göttingen University Medical Center Goettingen Exercise Intolerance in Heart Failure NCT03775577n/a1 site📍 Baltimore Johns Hopkins University A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF) NCT07795814Phase 228 sites📍 Birmingham📍 Little Rock📍 Beverly Hills Edgewise Therapeutics, Inc. · Tests: EDG-15400 25 mg, Placebo to match EDG-15400 25 mg or 50 mg, EDG-15400 50 mg Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition NCT06409585n/a1 site📍 Edinburgh University of Edinburgh · Tests: 68Ga-FAPI or 18F-AlF-FAPI cardiac PET-MR, Echocardiogram, Cardiac MRI Muscle Blood Flow Regulation in HFpEF NCT05115890NA1 site📍 Salt Lake City VA Office of Research and Development · Tests: Exercise training Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction NCT05174351NA1 site📍 Farmington UConn Health · Tests: beta blocker discontinuation
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