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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Heart Failure with Reduced Ejection Fraction

Assessment of CCM in HF With Higher Ejection Fraction NCT05064709NA67 sites๐Ÿ“ Birmingham๐Ÿ“ Mesa๐Ÿ“ Mesa Impulse Dynamics ยท Tests: Cardiac Contractility Modulation Therapy via OPTIMIZERโ„ข Smart Mini System, OPTIMIZERโ„ข Smart Mini System Demographic, Clinical, Biological, Treatment Characteristics and Cardiovascular Events of Patients With Heart Failure in Vietnam: a Multicenter Prospective Observational Study NCT06516562n/a1 site๐Ÿ“ Ho Chi Minh City University Medical Center Ho Chi Minh City (UMC) ยท Tests: Optimal treatment Exercise Capacity Improvement by Conduction System Pacing in heArt Failure patieNts Without Compelling CRT inDication NCT06278844NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: Conduction system pacing, Right ventricular apical pacing A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity NCT07567001Phase 3838 sites๐Ÿ“ Alexander City๐Ÿ“ Birmingham๐Ÿ“ Fairhope Novo Nordisk A/S ยท Tests: NNC0487-0111, Placebo Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity NCT07037459Phase 3657 sites๐Ÿ“ Birmingham๐Ÿ“ Dothan๐Ÿ“ Fairhope Amgen ยท Tests: Maridebart cafraglutide, Placebo Empagliflozin in Heart Failure with Reduced Ejection Fraction and End Stage Renal Disease NCT06249932Phase 42 sites๐Ÿ“ Hsinchu๐Ÿ“ Taipei National Taiwan University Hospital ยท Tests: Empagliflozin 25 MG, Placebo Eccentric Muscle Training in Cardiac Rehabilitation NCT07636343NA1 site๐Ÿ“ Edegem University Hospital, Antwerp ยท Tests: eccentric bike training, eccentric overload training, aerobic treadmill training, aerobic bike training, traditional dyโ€ฆ Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score NCT07490067Phase 41 site๐Ÿ“ Ann Arbor University of Michigan ยท Tests: Metoprolol Succinate, Beta-Blocker Polygenic Score, Illumina Infinium Global Diversity Array with Enhanced Pharmacogenoโ€ฆ Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction NCT05828719NA1 site๐Ÿ“ Seoul Samsung Medical Center ยท Tests: Percutaneous coronary intervention Predictive Factors of Response to Phase II Cardiac Rehabilitation in Heart Failure With Reduced Ejection Fraction NCT07164911n/a1 site๐Ÿ“ Corbie Centre Hospitalier de Corbie The CardioClip Study NCT06241430NA1 site๐Ÿ“ New York Columbia University ยท Tests: CardioMEMS SHengXIaN-QuYu DEcoction in Heart Failure With Reduced and Mildly Reduced Ejection Fraction NCT05583773Phase 426 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing China-Japan Friendship Hospital ยท Tests: ShengXian-QuYu Decoction, Placebo Effect of Pre-Hospital ARNI Therapy on Short-Term Outcomes in HFrEF NCT07347925n/a1 site๐Ÿ“ Al Mansurah Future University in Egypt ยท Tests: Prehospital ARNI use, No prehospital ARNI use Lumacaftor Yields Reversal of Impaired Cerebral Blood Flow in Heart Failure Patients NCT07695090Phase 22 sites๐Ÿ“ Toronto๐Ÿ“ Toronto Qanatpharma AG ยท Tests: Lumacaftor 200 MG, Placebo A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease NCT07214376NA18 sites๐Ÿ“ Tucson๐Ÿ“ New Haven๐Ÿ“ Weston Pulnovo Medical, Inc. ยท Tests: Pulmonary Artery Denervation (PADN), Sham procedure control The FOCUS-ADHF Registry NCT06726109n/a4 sites๐Ÿ“ Genk๐Ÿ“ Rivoli๐Ÿ“ Turin ASL Cittร  di Torino Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure NCT03480633n/a1 site๐Ÿ“ Boston Massachusetts General Hospital Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure NCT06342492n/a1 site๐Ÿ“ Overland Park Kansas City Heart Rhythm Research Foundation ยท Tests: Coronary Sinus Lead Revision Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure NCT06552637NA5 sites๐Ÿ“ Indianapolis๐Ÿ“ Tulsa๐Ÿ“ Philadelphia VisCardia Inc. ยท Tests: Synchronized Diaphragmatic Stimulation Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF NCT06078436NA1 site๐Ÿ“ Seoul Min-Seok Kim ยท Tests: Pulmonary artery catheter Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy NCT06128980Phase 2, Phase 31 site๐Ÿ“ Copenhagen Herlev and Gentofte Hospital ยท Tests: GDMT Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study) NCT07347197Phase 1, Phase 25 sites๐Ÿ“ Tsukuba๐Ÿ“ Kawasaki๐Ÿ“ Matsumoto Heartseed Inc. ยท Tests: HS-005 Ketones, SGLT2, HFrEF NCT06229678EARLY Phase 11 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Empagliflozin 25 MG Oral Tablet, Placebo, Acipimox 250 Mg Oral Capsule Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes NCT06108076EARLY Phase 11 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Ketone Monoester (KE) AI-Based Monitoring System for Chronic Heart Failure With Advanced Wearable and Mini-Invasive Devices NCT06909682n/a1 site๐Ÿ“ Salerno University of Salerno ยท Tests: Intervention Group (Device Group - AI-Based Remote Monitoring), Standard Clinical Follow-Up Study to Collect High-Resolution ECG Data and Patient Insights on Heart Failure Care NCT06809686n/a2 sites๐Ÿ“ London๐Ÿ“ London Richmond Research Institute A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) NCT06991257Phase 2150 sites๐Ÿ“ Beverly Hills๐Ÿ“ Lake Forest๐Ÿ“ Santa Maria Pfizer ยท Tests: Placebo, Low Dose PF-07328948, Medium Dose PF-07328948, High Dose PF-07328948 BAROSTIM THERAPYโ„ข in Heart Failure With Reduced Ejection Fraction NCT02880618n/a30 sites๐Ÿ“ Hamburg๐Ÿ“ Bad Oeynhausen๐Ÿ“ Berlin CVRx, Inc. ยท Tests: Barostim Neoโ„ข System Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator NCT06964464Phase 413 sites๐Ÿ“ Scottsdale๐Ÿ“ Rome๐Ÿ“ Shawnee Mission University of Rochester ยท Tests: Metoprolol Succinate, Carvedilol Resistance Exercise With Blood Flow Restriction by Vascular Occlusion on Myocardial Function in Heart Failure With Reduced Ejection Fraction NCT07118410NA1 site๐Ÿ“ Nรฎmes Centre Hospitalier Universitaire de Nฤซmes ยท Tests: Application of a vascular restriction device during resistance training
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