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30 recruiting trials

for Metabolic Dysfunction-associated Steatohepatitis

Spleen Stiffness Measurement for the Detection of Advanced Fibrosis NCT07440511n/a1 site๐Ÿ“ Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS The Development of MASLD Among Survivors of Breast or Colorectal Cancer NCT07280143n/a1 site๐Ÿ“ Bern University of Bern Association of HsCAR with MAFLD and Liver Fibrosis: a Cross-sectional Study NCT05974904n/a1 site๐Ÿ“ Chongqing Chongqing Medical University ยท Tests: high-sensitivity C-reactive protein to albumin ratio Diagnostic Value of the Liver Inflammation Index for MASH in Patients With T2DM and MAFLD NCT07632677n/a22 sites๐Ÿ“ Bengbu๐Ÿ“ Hefei๐Ÿ“ Wuhu The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: iLivTouch (Vibration-controlled transient elastography) Digital Early Warning System for Acute Lung Injury in Liver Surgery NCT07070362n/a4 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Chongqing Beijing Tsinghua Chang Gung Hospital Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease NCT05332613NA1 site๐Ÿ“ New York Weill Medical College of Cornell University ยท Tests: TRE plus SOC, SOC, TRE EVOO and Metabolic Liver Health in MASLD NCT07412444NA1 site๐Ÿ“ Castellana Grotte Azienda Ospedaliera Specializzata in Gastroenterologia Saveโ€ฆ ยท Tests: Oil Supplementation - 3 tablespoons of oil, 9 Tablespoons of Oil A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH NCT06920043Phase 230 sites๐Ÿ“ Chandler๐Ÿ“ Mesa๐Ÿ“ Tucson GlaxoSmithKline ยท Tests: Efimosfermin, Placebo Cardiac Dysfunction in Patients with Fatty Liver Disease NCT06386094n/a1 site๐Ÿ“ Chandigarh Post Graduate Institute of Medical Education and Research, โ€ฆ ยท Tests: Echocardiographic assessment Resmiterom Efficacy & Safety in Patients With MASH NCT07249788Phase 41 site๐Ÿ“ Rawalpindi Nabiqasim Industries (Pvt) Ltd ยท Tests: Resmetirom A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH NCT07221227Phase 391 sites๐Ÿ“ Chandler๐Ÿ“ Tucson๐Ÿ“ Little Rock GlaxoSmithKline ยท Tests: Efimosfermin alfa, Efimosfermin alfa, Placebo The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) NCT07093346NA3 sites๐Ÿ“ Nottingham๐Ÿ“ Nottingham๐Ÿ“ Nottingham University of Nottingham ยท Tests: Pectin, Cocoa Powder, Magnetic Resonance Imaging with Contrast COmmencing Menopausal HOrmone Replacement Therapy and the Effect on Metabolic-dysfunction Associated Steatotic Liver Disease: a Pilot Mechanistic Study NCT06704516Phase 11 site๐Ÿ“ Oxford University of Oxford ยท Tests: Menopausal hormone therapy Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo) NCT07330830n/a3 sites๐Ÿ“ Cayenne๐Ÿ“ Pointe-ร -Pitre๐Ÿ“ Saint-Denis Centre Hospitalier Universitaire de la Guadeloupe Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis NCT07270601NA1 site๐Ÿ“ Seattle ContextVision AB ยท Tests: Verasonics NXT Data Acquisition System, Philips EPIQ Elite, EchoSense FibroScan, Philips 3T Ingenia Elition Pioglitazone and Empagliflozin for Fatty Liver Disease in Type 2 Diabetes NCT06989723Phase 41 site๐Ÿ“ Seongnam-si Seoul National University Bundang Hospital ยท Tests: Pioglitazone 15 MG [Actos], Empagliflozin 10 MG [Jardiance], Empagliflozin 10 MG [Jardiance] + Pioglitazone 15 MG [Actoโ€ฆ A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition NCT05519475Phase 271 sites๐Ÿ“ Flagstaff๐Ÿ“ Peoria๐Ÿ“ Tucson Regeneron Pharmaceuticals ยท Tests: ALN-HSD, Placebo A Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) NCT07145151Phase 21 site๐Ÿ“ Beijing The United Bio-Technology (Hengqin) Co., Ltd. ยท Tests: UBT251, Placebo A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis NCT06461208Phase 323 sites๐Ÿ“ Basildon๐Ÿ“ Bournemouth๐Ÿ“ Bristol King's College London ยท Tests: Encapsulated FMT, Placebo High-Risk Transcriptome Molecular Prediction Study of MASH-Associated Colorectal Polyps NCT07463287n/a1 site๐Ÿ“ Shanghai Shanghai East Hospital Development of Microbial Therapeutics for Metabolic-associated Fatty Liver Disease: From Mechanistic Investigations to Clinical Trials NCT06873165NA1 site๐Ÿ“ Taipei National Taiwan University Hospital ยท Tests: Probiotics, Placebo A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) NCT05648214Phase 1, Phase 26 sites๐Ÿ“ Glendale๐Ÿ“ Los Angeles๐Ÿ“ Miami Regeneron Pharmaceuticals ยท Tests: ALN-PNP, Placebo (PB) Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial NCT06138821NA2 sites๐Ÿ“ Boston๐Ÿ“ Morgantown Pichamol Jirapinyo, MD, MPH ยท Tests: ESG + lifestyle modification, Lifestyle modification Automated Passive Case-Finding for Advanced Liver Fibrosis in MASLD: The LiverSeek Programme NCT07658755n/a1 site๐Ÿ“ Madrid Hospital General Universitario Gregorio Maraรฑon Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly NCT07068191NA1 site๐Ÿ“ Tyumen Phenomen Pharma ยท Tests: Dietary supplement "Gepaktiv", UDCA (Ursodeoxycholic acid), Ademetionine A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH) NCT07325526Phase 227 sites๐Ÿ“ Chandler๐Ÿ“ Coronado๐Ÿ“ La Mesa Boehringer Ingelheim ยท Tests: BI 3802876, Placebo A Study of HRS-4729 Injection and HRS9531 Injection in Participants With Metabolic Dysfunction-Associated Steatohepatitis NCT07660848Phase 22 sites๐Ÿ“ Beijing๐Ÿ“ Zhengzhou Fujian Shengdi Pharmaceutical Co., Ltd. ยท Tests: HRS-4729 Injection, HRS9531 Injection, HRS-4729 Injection Placebo, HRS9531 Injection Placebo Liver Steatosis and Fibrosis in Non-Celiac Wheat Sensitivity Patients: a Prospective Study NCT07750535n/a2 sites๐Ÿ“ Palermo๐Ÿ“ Palermo University of Palermo ยท Tests: Prevalence and severity of liver steatosis and fibrosis, LIVERAGEโ„ข: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis NCT06632444Phase 3531 sites๐Ÿ“ Birmingham๐Ÿ“ Peoria๐Ÿ“ Scottsdale Boehringer Ingelheim ยท Tests: Survodutide, Placebo Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial NCT07193927Phase 21 site๐Ÿ“ Girona AB Biotics, SA ยท Tests: Lactiplantibacillus plantarum Probiotic Mixture, Placebo comparator containing maltodextrin
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