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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Rectal Neoplasm Malignant

SBRT + PD-1 Antibody in Unresectable Locally Recurrent Rectal Cancer๏ผˆSPARKLE๏ผ‰ NCT06767007Phase 21 site๐Ÿ“ Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University ยท Tests: Stereotactic Body Radiation Therapy (SBRT), PD1, Chemotherapy The Development of MASLD Among Survivors of Breast or Colorectal Cancer NCT07280143n/a1 site๐Ÿ“ Bern University of Bern DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Alkmaar๐Ÿ“ Amstelveen Leiden University Medical Center ยท Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)โ€ฆ Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery NCT03051464Phase 2, Phase 34 sites๐Ÿ“ Dallas๐Ÿ“ Montreal๐Ÿ“ Montreal Sir Mortimer B. Davis - Jewish General Hospital ยท Tests: Complete responders and Non-complete responders, Chemoradiation + EBRT Boost, Chemoradiation + HDRBT Boost Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors NCT04222413Phase 12 sites๐Ÿ“ Fairway๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Metarrestin A Prospective, Single-Arm Clinical Study of a Dietary Supplement for the Prevention of Acute Radiation-Induced Rectal Injury During Neoadjuvant Chemoradiotherapy for Rectal Cancer NCT07802002NA1 site๐Ÿ“ Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University ยท Tests: Tributyrin Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery NCT04103372NA23 sites๐Ÿ“ Reading๐Ÿ“ Amersham๐Ÿ“ London Imperial College London ยท Tests: MRI scan, Radiologist training Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC NCT07448077Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: Experimental: short-course radiotherapy and immunotherapy, Chemoradiotherapy CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors NCT05733000Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Devimistat, Fluorouracil, Gemcitabine Hydrochloride Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies NCT04282044Phase 13 sites๐Ÿ“ Scottsdale๐Ÿ“ La Jolla๐Ÿ“ Stanford BioEclipse Therapeutics ยท Tests: CRX100 suspension for infusion, Fludarabine, Cyclophosphamide Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma NCT05752136Phase 31 site๐Ÿ“ Hangzhou Sir Run Run Shaw Hospital ยท Tests: Envafolimab Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision NCT06279299NA1 site๐Ÿ“ Beijing National Cancer Center, China ยท Tests: lateral pelvic lymph node dissection Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer NCT06530303Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamide, Fludarabine, Interleukin-2, Pembrolizumab An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response NCT04796818NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Diffusion Weighted Imaging Neoadjuvant Chemoradiotherapy Plus Tislelizumab With or Without Probio-M9 in pMMR/MSS Locally Advanced Rectal Cancer NCT07458529Phase 21 site๐Ÿ“ Beijing Seventh Medical Center of PLA General Hospital ยท Tests: CRT+PD-1 inhibitor+Probio-M9, CRT+PD-1 inhibitor+placebo ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer NCT06589388n/a1 site๐Ÿ“ Ho Chi Minh City Gene Solutions Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy NCT05965531Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Trifluridine/Tipiracil, intensity-modulated radiotherapy Colorectal Cancer Screnning Colonoscopy Under Hypnosis NCT05051046NA1 site๐Ÿ“ Angers University Hospital, Tours ยท Tests: Colonoscopy under hypnosis Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer NCT06613165n/a1 site๐Ÿ“ Xi'an Xijing Hospital Iparomlimab/Tuvonralimab Integrating With Total Neoadjuvant Therapy for pMMR/MSS Locally Advanced Rectal Cancer (IT-TNT) NCT07026422Phase 21 site๐Ÿ“ Jinan Shandong Cancer Hospital and Institute ยท Tests: Total neoadjuvant therapy integrating iparomlimab/tuvonralimab with chemoradiotherapy Stereotactic Ablative Radiotherapy (SABR) for the Treatment of Patients With Metastatic Cancer, ID-COMET Trial NCT06563388Phase 31 site๐Ÿ“ Buffalo Roswell Park Cancer Institute ยท Tests: Stereotactic Ablative Radiotherapy, Best Practice Immunotherapy in Patients With Early dMMR Rectal Cancer NCT05732389Phase 25 sites๐Ÿ“ Aalborg๐Ÿ“ Aarhus๐Ÿ“ Copenhagen Odense University Hospital ยท Tests: Nivolumab, Ipilimumab Watch and Wait as Treatment for Patients With Rectal Cancer NCT03125343NA2 sites๐Ÿ“ Gothenburg๐Ÿ“ Stockholm Sahlgrenska University Hospital ยท Tests: endoscopy, Surgery, MRI Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer NCT04288999Phase 345 sites๐Ÿ“ Chiba๐Ÿ“ Gifu๐Ÿ“ Hidaka National Cancer Center Hospital East ยท Tests: Chemotherapy, Preoperative radiotherapy, Procedure Diagnosis of Multiple Cancer and Monitoring of Minimal Residual Tumors After Treatment Using Blood and High-Sensitivity Genetic Analysis Techniques NCT07035587n/a1 site๐Ÿ“ Seoul Yonsei University ยท Tests: Serial Blood Sampling for Molecular Profiling, One-Time Blood Sampling for Molecular Profiling Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer NCT04098471NA1 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: transanal local excision following radiotherapy, TME CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites๐Ÿ“ Denver๐Ÿ“ Chicago๐Ÿ“ Grand Rapids Context Therapeutics Inc. ยท Tests: CT-95 A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer NCT06637462NA6 sites๐Ÿ“ Middletown๐Ÿ“ Montvale๐Ÿ“ Commack Memorial Sloan Kettering Cancer Center ยท Tests: Endoscopy Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScoreยฎ in Patients With Non Metastatic Rectal Cancer NCT06536127NA1 site๐Ÿ“ Avignon Institut Sainte Catherine ยท Tests: Blood samples Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors NCT04771520Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Avapritinib
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