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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Rhinosinusitis Chronic

Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery NCT06776042NA1 site📍 Brussels Cliniques universitaires Saint-Luc- Université Catholique d… · Tests: Nasal brushing of the olfactory cleft, Smell testing 3D Printing to Improve Nasal Irrigation Outcome NCT06118554NA1 site📍 Columbus Ohio State University · Tests: Irrigation head position Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS). NCT07184684Phase 2, Phase 31 site📍 Helsingborg Region Skane · Tests: Sinonasal microbiome transplant procedure., Placebo saline transplant Propel Drug-Eluting Sinus Implant Family IBUKI Cohort NCT07546682n/a1 site📍 Asahikawa Medtronic · Tests: None, observational standard of care study Sinus Disease in Young Children With Cystic Fibrosis NCT06191640n/a6 sites📍 Aurora📍 Iowa City📍 Kansas City University of California, Los Angeles · Tests: Ivacaftor or elexacaftor/tezacaftor/ivacaftor Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial NCT06750302Phase 1, Phase 21 site📍 Vancouver St. Paul's Hospital, Canada · Tests: Methoxyflurane - Penthrox, Placebo Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis NCT05427695Phase 21 site📍 Chicago University of Illinois at Chicago · Tests: Lactobacillus sakei proBio65, Isotonic Saline Solution Effect of Chinese Herbal Medicine Nasal Irrigation on the Postoperative Care of Chronic Rhinosinusitis NCT07340411Phase 21 site📍 Taichung Taichung Veterans General Hospital · Tests: Chinese herbal medicine Powder, Salt Powder Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal Polyps NCT07860411n/a1 site📍 Sanliurfa Harran University · Tests: Nasal polyp tissue and blood sampling, Nasal mucosa and blood sampling Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label NCT07689773Phase 21 site📍 Charleston Medical University of South Carolina · Tests: Trigeminal Nerve Stimulation-enhanced Smell Training The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS) NCT05882903Phase 24 sites📍 Sydney📍 Brisbane📍 Adelaide Oticara Australia PTY LTD · Tests: Betamethasone Dipropionate Nasal Cream 0.0644%, Pre-filled syringe and applicator device Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. NCT06892704n/a1 site📍 Chicago Northwestern University · Tests: Dupilumab - Standard Dose Real Life Study of Biologicals in Patients With Severe CRSwNP NCT05938972n/a1 site📍 Ghent University Hospital, Ghent · Tests: Mepolizumab Balloon Sinuplasty Efficiency in Maxillary Rhinosinusitis. NCT04645511NA1 site📍 Tampere Tampere University Hospital · Tests: Balloon sinuplasty of maxillary sinuses, Sham surgery Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis NCT03439865EARLY Phase 11 site📍 Birmingham University of Alabama at Birmingham · Tests: Ivacaftor, standard of care treatment Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP NCT06398873n/a1 site📍 Vienna Medical University of Vienna · Tests: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT] Real-Life Chronic Rhinosinusitis Outcome Registry NCT04670172n/a13 sites📍 Graz📍 Vienna📍 Brussels Change Accelerator in Respiratory Care Using Navigation to Improve Accuracy of Maxillary Balloon Sinusotomy NCT06567821Phase 2, Phase 31 site📍 Los Angeles Cedars-Sinai Medical Center · Tests: RELIEVA SPINPLUS® NAV Balloon Sinusplasty System Efficacy and Safety of Fully Resorbable Sinus Drug-eluting Stents in Patients With Eosinophilic Chronic Rhinosinusitis With Nasal Polyps After Surgery: A Prospective, Randomized Controlled Trial NCT07498374NA1 site📍 Xi'an Tang-Du Hospital · Tests: the fully degradable sinus stent, intranasal corticosteroids, oral corticosteroids Prospective, Non-interventional Single-arm Study With Tezepelumab to Investigate the Change in Clinical and Patient-reported Outcomes in Patients With CRSwNP in Real-world (PETRICHOR) NCT07633158n/a19 sites📍 Berlin📍 Bochum📍 Braunschweig AstraZeneca Mepolizumab and in Office-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). NCT07814924Phase 47 sites📍 Barakaldo📍 Jerez de la Frontera📍 Madrid Instituto de Investigación Marqués de Valdecilla · Tests: surgical arm, Mepolizumab 100 MG, combined arm Biologics in Chronic Rhinosinusitis With Nasal Polyposis NCT06824649Phase 43 sites📍 Gainesville📍 Portland📍 Charleston Medical University of South Carolina · Tests: Biologic Agents Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis NCT02038166n/a1 site📍 Birmingham University of Alabama at Birmingham A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) NCT06338995Phase 3202 sites📍 Birmingham📍 Birmingham📍 Huntsville Eli Lilly and Company · Tests: LY3650150, Placebo, Standard therapy for INCS A Phase I Study Evaluating the Safety, Tolerability, and Pharmacokinetics of VVN432 Nasal Spray NCT07259538Phase 11 site📍 Beijing VivaVision Biotech, Inc · Tests: 0.5% VVN432 Nasal Spray, 1% VVN432 Nasal Spray, Vehicle Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults NCT05157685Phase 313 sites📍 Bordeaux📍 Créteil📍 Le Kremlin-Bicêtre Centre Hospitalier Intercommunal Creteil · Tests: Azithromycin Oral Tablet, Placebo Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy NCT06996951Phase 31 site📍 Indianapolis Indiana University · Tests: STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID, CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis NCT05935683n/a1 site📍 Rozzano Italian Academy of Rhinology · Tests: Severe Uncontrolled Chronic Rhinosinusitis patients (CRS) Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps NCT06850805Phase 324 sites📍 Huntsville📍 Gilbert📍 Los Angeles Optinose US Inc. · Tests: OPN-375, Placebo Triamcinolone Nanocapsules After Endoscopic Nasal Surgery NCT07714525Phase 21 site📍 Minya Deraya University · Tests: Triamcinolone Acetonide-Loaded Polymeric Nanocapsules, Normal Saline Nasal Irrigation
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