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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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19 recruiting trials

for Sickle Cell Disease Vaso-occlusive Crisis

Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease NCT07274254Phase 312 sites📍 Bordeaux📍 Bordeaux📍 Lille Nantes University Hospital · Tests: Lidocain, Placebo, Standard of care Efficacy of Liberal Versus Restricted IV Fluid Approach in the Management of Sickle Cell Vaso-Occlusive Crisis NCT07188766NA2 sites📍 Dammam📍 Riyadh Imam Abdulrahman Bin Faisal University · Tests: Sodium Chloride (NaCl) 0.9 %, Sodium Chloride (NaCl) 0.9 % Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises NCT06184126NA1 site📍 Baltimore University of Maryland, Baltimore · Tests: Virtual Reality Headset and Hand-Held Controllers, Blindfolding and Noise Cancelling Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD) NCT07224360Phase 216 sites📍 Little Rock📍 Orange📍 Hollywood CSL Behring · Tests: Anumigilimab, Placebo Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults NCT07369024Phase 21 site📍 Torrance Mohsen Saidinejad · Tests: Sub-dissociative Ketamine Infusion, Normal Saline Placebo Infusion Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis NCT06699849Phase 230 sites📍 Oakland📍 Orange📍 Washington D.C. CSL Behring · Tests: CSL889, Placebo Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease NCT06635902Phase 21 site📍 Washington D.C. Suvankar Majumdar · Tests: L-citrulline, Placebo, L-citrulline Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study NCT04657822Phase 431 sites📍 Birmingham📍 Washington D.C.📍 Augusta Novartis Pharmaceuticals · Tests: Crizanlizumab Exploratory Study on Global Reflexology in Sickle Cell Disease NCT06619197NA1 site📍 Bron Hospices Civils de Lyon · Tests: Global reflexology Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease NCT06399107Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: Drug Product is administered by IV infusion following myeloablative conditioning with busulfan High-flow Oxygen for Vaso-occlusive Pain Crisis NCT03976180NA1 site📍 Créteil Assistance Publique - Hôpitaux de Paris · Tests: Stadard low-flow oxygen, HFNO with low FiO2 (21%-30%), HFNO with intermediate FiO2 (50%), HFNO with high FiO2 (100%) Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care NCT07246265NA6 sites📍 Tours📍 Créteil📍 Le Mans University Hospital, Tours · Tests: Injection of iohexol for glomerular filtration rate (GFR) measurement Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA. NCT07432867Phase 1, Phase 21 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: DREAM01 drug product, anti-inflammatory therapy Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients NCT07001189n/a1 site📍 Pointe-à-Pitre Centre Hospitalier Universitaire de la Guadeloupe Sickle Cell Improvement: Enhancing Care in the Emergency Department NCT05373771NA1 site📍 Milwaukee Medical College of Wisconsin · Tests: Care pathway Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease NCT03353584NA2 sites📍 Memphis📍 Memphis St. Jude Children's Research Hospital · Tests: Virtual Reality Therapy Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease NCT07001631NA1 site📍 Amsterdam Academisch Medisch Centrum - Universiteit van Amsterdam (AM… · Tests: Eye Movement Desensitization and Reprocessing (EMDR) Virtual Reality for SCD VOC NCT07674277NA1 site📍 Baltimore University of Maryland, Baltimore · Tests: Sham 2D Headset Control, Passive Immersive 3D Virtual Reality, Active Immersive Interactive 3D Virtual Reality A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) NCT06439082Phase 336 sites📍 Birmingham📍 Orange📍 Washington D.C. Novartis Pharmaceuticals · Tests: Crizanlizumab, Placebo
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