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30 recruiting trials

for Chronic Rhinosinusitis (Diagnosis)

Sinus Disease in Young Children With Cystic Fibrosis NCT06191640n/a6 sites๐Ÿ“ Aurora๐Ÿ“ Iowa City๐Ÿ“ Kansas City University of California, Los Angeles ยท Tests: Ivacaftor or elexacaftor/tezacaftor/ivacaftor Topical Probiotic Sinus Irrigations for Treating Chronic Sinusitis NCT05427695Phase 21 site๐Ÿ“ Chicago University of Illinois at Chicago ยท Tests: Lactobacillus sakei proBio65, Isotonic Saline Solution Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis With Nasal Polyps NCT07860411n/a1 site๐Ÿ“ Sanliurfa Harran University ยท Tests: Nasal polyp tissue and blood sampling, Nasal mucosa and blood sampling Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label NCT07689773Phase 21 site๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: Trigeminal Nerve Stimulation-enhanced Smell Training The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS) NCT05882903Phase 24 sites๐Ÿ“ Sydney๐Ÿ“ Brisbane๐Ÿ“ Adelaide Oticara Australia PTY LTD ยท Tests: Betamethasone Dipropionate Nasal Cream 0.0644%, Pre-filled syringe and applicator device Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients. NCT06892704n/a1 site๐Ÿ“ Chicago Northwestern University ยท Tests: Dupilumab - Standard Dose Balloon Sinuplasty Efficiency in Maxillary Rhinosinusitis. NCT04645511NA1 site๐Ÿ“ Tampere Tampere University Hospital ยท Tests: Balloon sinuplasty of maxillary sinuses, Sham surgery Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis NCT03439865EARLY Phase 11 site๐Ÿ“ Birmingham University of Alabama at Birmingham ยท Tests: Ivacaftor, standard of care treatment Real-Life Chronic Rhinosinusitis Outcome Registry NCT04670172n/a13 sites๐Ÿ“ Graz๐Ÿ“ Vienna๐Ÿ“ Brussels Change Accelerator in Respiratory Care Biologics in Chronic Rhinosinusitis With Nasal Polyposis NCT06824649Phase 43 sites๐Ÿ“ Gainesville๐Ÿ“ Portland๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: Biologic Agents Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis NCT02038166n/a1 site๐Ÿ“ Birmingham University of Alabama at Birmingham Evaluation of the Efficacy of Azithromycin in Idiopathic Purulent Oedematous Sinusitis in Adults NCT05157685Phase 313 sites๐Ÿ“ Bordeaux๐Ÿ“ Crรฉteil๐Ÿ“ Le Kremlin-Bicรชtre Centre Hospitalier Intercommunal Creteil ยท Tests: Azithromycin Oral Tablet, Placebo Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy NCT06996951Phase 31 site๐Ÿ“ Indianapolis Indiana University ยท Tests: STOP NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID, CONTINUE NASAL SALINE IRRIGATION WITH OR WITHOUT STEROID Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis NCT05935683n/a1 site๐Ÿ“ Rozzano Italian Academy of Rhinology ยท Tests: Severe Uncontrolled Chronic Rhinosinusitis patients (CRS) Triamcinolone Nanocapsules After Endoscopic Nasal Surgery NCT07714525Phase 21 site๐Ÿ“ Minya Deraya University ยท Tests: Triamcinolone Acetonide-Loaded Polymeric Nanocapsules, Normal Saline Nasal Irrigation A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782957Phase 34 sites๐Ÿ“ Sherman Oaks๐Ÿ“ Greenville๐Ÿ“ Plano GlaxoSmithKline ยท Tests: GSK5784283, Placebo, Standard of Care Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP NCT05094570Phase 41 site๐Ÿ“ Charlottesville University of Virginia ยท Tests: Dupilumab Prefilled Syringe BIOlogics in Severe Nasal POlyposis SurvEy.: a French Registry NCT06501807NA2 sites๐Ÿ“ Lille๐Ÿ“ Lille University Hospital, Lille ยท Tests: Biologic treatments available in Chronic Rhinosinusitis with Nasal Polyps (dupilumab, mepolizumab and benralizumab accoโ€ฆ Complete Remission After Treatment With Biologics for Nasal Polyps NCT07268313Phase 46 sites๐Ÿ“ Copenhagen๐Ÿ“ Hillerรธd๐Ÿ“ Kรธge Copenhagen University Hospital, Rigshospitalet ยท Tests: DUPIXENTยฎ, NUCALAยฎ, Dupi discontinuation, Mepo discontinuation A Study to Assess the Efficacy and Safety of GSK5784283 (Felcorekibart) in Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) NCT07782970Phase 33 sites๐Ÿ“ Los Angeles๐Ÿ“ Tulsa๐Ÿ“ San Juan GlaxoSmithKline ยท Tests: GSK5784283, Placebo, Standard of Care Effect of Full-House ESS With Nasopharyngeal Lymphoid Tissue Ablation on Nasal Polyps NCT07245329NA1 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Nasopharyngeal Lymphoid Tissue Ablation, Full-House Endoscopic Sinus Surgery Cognitive and Immunologic Profiles of Patients With Olfactory Dysfunction After Smell Training NCT07681973NA1 site๐Ÿ“ Cleveland The Cleveland Clinic ยท Tests: Smell Training Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough NCT05110144Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Duloxetine 30 MG, Duloxetine 60 MG, Amitriptyline 25 MG, Amitriptyline 50 MG, Placebo 30 MG Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis NCT06986629NA1 site๐Ÿ“ Cairo Cairo University ยท Tests: pulsed electromagnetic therapy, Photobiostimulation, Self-sinus massage technique Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms NCT07262450NA32 sites๐Ÿ“ Bordeaux๐Ÿ“ Bourg-la-Reine๐Ÿ“ Cabourg Laboratoire de la Mer ยท Tests: Respimerยฎ Hygiene-Prevention -Baby, kids, adults, Respimerยฎ Hygiene-Prevention Kids, adults, Respimerยฎ Decongestion Babโ€ฆ Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps NCT06129552n/a1 site๐Ÿ“ Leuven Universitaire Ziekenhuizen KU Leuven ยท Tests: Conchotomy, aesthetic nose surgery or functional endoscopic sinus operation Impact of Sinus Surgery on Individuals With Cystic Fibrosis NCT04469439n/a9 sites๐Ÿ“ Los Angeles๐Ÿ“ Stanford๐Ÿ“ Aurora University of California, Los Angeles Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial Asthma NCT05708300n/a2 sites๐Ÿ“ Thessaloniki๐Ÿ“ Thessaloniki Aristotle University Of Thessaloniki ยท Tests: Mepolizumab 100 MG [Nucala] Establishing Personalized Phage Therapy and Its Comparative Cost in Difficult-to-treat Infections (EPHICACI) NCT06368388n/a1 site๐Ÿ“ Leuven Universitaire Ziekenhuizen KU Leuven ยท Tests: Prospective data collection phage therapy, Prospective data collection standard-of-care In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps NCT02975310NA4 sites๐Ÿ“ Vancouver๐Ÿ“ London๐Ÿ“ Ottawa Ottawa Hospital Research Institute ยท Tests: Endoscopic polypectomy in clinic (EPIC), Endoscopic Sinus Surgery (ESS), General Anesthesia, Local and topical anesthesโ€ฆ
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