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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Epilepsies, Focal

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3) NCT05716100Phase 398 sites๐Ÿ“ Little Rock๐Ÿ“ Downey๐Ÿ“ Los Angeles Xenon Pharmaceuticals Inc. ยท Tests: XEN1101, Placebo Temporal Interference Brain Stimulation for Adults With Drug-Resistant Epilepsy Undergoing Stereo-EEG Monitoring NCT07764718NA1 site๐Ÿ“ Durham Duke University ยท Tests: Temporal Interference Stimulation, Direct Electrical Stimulation Evaluation of New Flexible High-density Intra-operative ECoG Electrodes for Epilepsy Surgery. ( EpiGrid ) NCT06205160NA1 site๐Ÿ“ Utrecht Neurosoft Bioelectronics SA ยท Tests: SOFT ECoG subdural grid electrode Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database NCT02107989n/a1 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ ยท Tests: MRI, MEG Impact of Confirmed Autoimmune Encephalitis on Brain Glucose Metabolism NCT06079294NA1 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris ยท Tests: FDG PET Sleep Architecture & Cognition in Focal Epilepsy NCT05794295NA1 site๐Ÿ“ Sacramento University of California, Davis ยท Tests: Acoustic Stimulation (AS), SHAM Stimulation Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain NCT03268824n/a1 site๐Ÿ“ Paris Fondation Ophtalmologique Adolphe de Rothschild ยท Tests: Electroencephalogram (EEG), Diffusion Tensor imaging, Language assessment LIFUS For Neurological Disorders NCT07417280NA1 site๐Ÿ“ Toronto University Health Network, Toronto ยท Tests: LIFUS, Sham LIFUS Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures NCT07594119Phase 313 sites๐Ÿ“ Huntsville๐Ÿ“ Bentonville๐Ÿ“ Colorado Springs Rapport Therapeutics Inc. ยท Tests: RAP-219, RAP-219, Placebo Focused Ultrasound for Drug-resistant Epilepsy NCT06292494NA1 site๐Ÿ“ Taipei Taipei Veterans General Hospital, Taiwan ยท Tests: Exablate 4000 Transcranial MRgfUS System Spatial Scene Recognition Memory in Epilepsy Surgery NCT07580183NA2 sites๐Ÿ“ Sacramento๐Ÿ“ Atlanta University of California, Davis ยท Tests: Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimagโ€ฆ Intracerebral Electrical Stimulation and the Optimisation of Presurgical Planning in Drug-refractory Partial Epilepsy NCT03738072NA1 site๐Ÿ“ Toulouse University Hospital, Toulouse ยท Tests: StiMiC stimulation condition The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy NCT07095933EARLY Phase 11 site๐Ÿ“ Beijing Xuanwu Hospital, Beijing ยท Tests: Everolimus Real-world Clinical Response to Cenobamate Early add-on in France, Germany and Spain NCT06716801n/a1 site๐Ÿ“ Paris Aziende Chimiche Riunite Angelini Francesco S.p.A ยท Tests: Cenobamate Study for the Diagnosis and Treatment of Drug-resistant Focal Epilepsies NCT06794606n/a1 site๐Ÿ“ Milan Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy NCT05518578Phase 210 sites๐Ÿ“ Jacksonville๐Ÿ“ Miami๐Ÿ“ Randwick Supernus Pharmaceuticals, Inc. ยท Tests: SPN-817 An Open Label Trial to Evaluate the Efficacy and Safety of PRAX-628 in Adults With Focal Onset or Tonic-Clonic Seizures NCT06908356Phase 211 sites๐Ÿ“ Phoenix๐Ÿ“ Miami Lakes๐Ÿ“ Bethesda Praxis Precision Medicines ยท Tests: 30mg PRAX-628 Mos-FED (Mosaicism in Focal Epilepsy Cortical Dysplasia Tissue) NCT06053671NA1 site๐Ÿ“ London King's College Hospital NHS Trust ยท Tests: Blood and nasal swab sampling Breathing Rescue for SUDEP Prevention NCT05981755NA1 site๐Ÿ“ Houston The University of Texas Health Science Center, Houston ยท Tests: Breathing tasks, Brain mapping with stimulation Exploring the Characteristics of Epileptogenic Foci in Drug-Resistant Epilepsy Based on Multimodal Imaging Technology NCT06557720n/a1 site๐Ÿ“ Xi'an Xijing Hospital High-density Flexible ฮผECoG for Epilepsy Surgery - A Single-Arm ECT NCT07656857NA1 site๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: Using High-density Flexible microElectrocorticography for intraoperative monitoring Thalamic Recordings in Children Undergoing SEEG NCT06453759NA1 site๐Ÿ“ London Great Ormond Street Hospital for Children NHS Foundation Trโ€ฆ ยท Tests: Additional electrodes into bilateral anterior, centromedian and pulvinar thalamic nuclei Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy)) NCT05135091Phase 335 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Tucson Neurona Therapeutics ยท Tests: NRTX-1001, NRTX-1001, Sham Comparator Electroclinical Correlation of Anxiety NCT05393518NA1 site๐Ÿ“ Bordeaux University Hospital, Bordeaux ยท Tests: Anxiety-induced task, Neuropsychiatric assessment A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome NCT07013331NA1 site๐Ÿ“ Bron Hospices Civils de Lyon ยท Tests: [18F]MPPF PET-MRI Study of Transcranial Direct Current Stimulation to Treat Epilepsy NCT05673915NA1 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: ActivaDose II 0.1 mA transcranial direct current stimulation (tDCS), ActivaDose II 2.0 mA transcranial direct current sโ€ฆ An Open-label Study to Evaluate Safety, Tolerability, and Efficacy of CB03-154 in Subjects Diagnosed With Epilepsy NCT07238868Phase 21 site๐Ÿ“ Melbourne Shanghai Zhimeng Biopharma, Inc. ยท Tests: CB03-154 A Clinical Study on the Efficacy and Safety of Zonisamide as a First Add-On Treatment in Epileptic Seizures NCT06967012Phase 41 site๐Ÿ“ Nantong Affiliated Hospital of Nantong University ยท Tests: Oral Zonisamide Therapy Changes in Attentional Control After a Focal Seizure. NCT06466681n/a1 site๐Ÿ“ Lille University Hospital, Lille ยท Tests: All included subjects Mapping Epileptic Networks Using Multimodal Imaging NCT06202976n/a1 site๐Ÿ“ Paris Imagine Institute ยท Tests: Secondary data collection
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