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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery NCT04136717NA1 site๐Ÿ“ Quรฉbec Franรงois Lellouche ยท Tests: Washout period, NIV - FreeO2, Nasal High flow Oxygen therapy - FreeO2, CPAP - Oxygen constant flow, CPAP - FreeO2 Sonographic Diaphragm Function in AECOPD NCT05671198n/a1 site๐Ÿ“ Zwolle Isala ยท Tests: Ultrasound of the diaphragm COPD Exacerbation Follow Up NCT07118306n/a5 sites๐Ÿ“ Park Ridge๐Ÿ“ Cherry Hill๐Ÿ“ Philadelphia Viz.ai, Inc. Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa NCT04427826Phase 1, Phase 21 site๐Ÿ“ Grenoble University Hospital, Grenoble ยท Tests: Morphine hydrochloride Ultrasound of the Diaphragm Excursion Ratio as Physiological Biomarker in Acute Exacerbations of Chronic Obstructive Pulmonary Disease NCT07259174n/a2 sites๐Ÿ“ Zwolle๐Ÿ“ Groningen Isala The CATALINA Study NCT05008081n/a22 sites๐Ÿ“ Linz๐Ÿ“ Vienna๐Ÿ“ Brussels Wim Janssens Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis NCT06114667NA3 sites๐Ÿ“ Montpellier๐Ÿ“ Nรฎmes๐Ÿ“ Poitiers University Hospital, Montpellier ยท Tests: Ventilatory support via nasal high flow, Ventilatory support via NIV A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD NCT07344285NA1 site๐Ÿ“ Shatin Chinese University of Hong Kong ยท Tests: Intervention Group, Usual Care Interoception and Symptom Perception in Acute COPD Exacerbation NCT07719231n/a1 site๐Ÿ“ Istanbul Saglik Bilimleri Universitesi ยท Tests: No Intervention: Observational Cohort The Effectiveness of Tele-pulmonary Rehabilitation Program on People With Chronic Obstructive Pulmonary Disease (COPD) After Hospitalization for Acute Exacerbation NCT07762157NA1 site๐Ÿ“ Hong Kong North District Hospital ยท Tests: Tele-pulmonary rehabilitation High Flow Nasal Oxygen for Exacerbation COPD NCT06084117NA4 sites๐Ÿ“ Delft๐Ÿ“ Rotterdam๐Ÿ“ Rotterdam Franciscus Gasthuis ยท Tests: HFNO, NIV Exploring How Viral Infections Affect People With Chronic Lung Disease NCT06625944n/a1 site๐Ÿ“ London Imperial College London Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS) NCT05958563NA15 sites๐Ÿ“ Angers๐Ÿ“ Bordeaux๐Ÿ“ Brest University Hospital, Angers ยท Tests: continuous positive airway pressure treatment Patients With Severe Acute Exacerbation of COPD Ans Admitted in ICU Register. NCT06257329n/a2 sites๐Ÿ“ Le Chesnay๐Ÿ“ Le Mans Alexis FERRE ยท Tests: register Neutrophil to Lymphocyte Ratio in Acute Exacerbation of Chronic Obstructive Pulmonary Disease NCT07125352n/a1 site๐Ÿ“ Cairo Ain Shams University ยท Tests: neutrophil lymphocyte ratio in COPD patients Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness NCT07536035n/a1 site๐Ÿ“ Singapore National University Hospital, Singapore Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) NCT06892210Phase 414 sites๐Ÿ“ Rรธnne๐Ÿ“ Copenhagen๐Ÿ“ Copenhagen Copenhagen Respiratory Research ยท Tests: Methylprednisolone (drug), Hydrocortisone Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients NCT03890224NA1 site๐Ÿ“ Paris Clinact ยท Tests: home ventilators Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital NCT06597331n/a1 site๐Ÿ“ Gothenburg Sahlgrenska University Hospital Rademikibart IV for Acute Asthma and COPD Exacerbation NCT07705737Phase 23 sites๐Ÿ“ Miami๐Ÿ“ Miami๐Ÿ“ St Louis Connect Biopharm LLC ยท Tests: Rademikibart Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease NCT05703919Phase 41 site๐Ÿ“ Aarhus N Central Denmark Region ยท Tests: Titrated Oxygen, Standard Oxygen DUET Versus Standard Interface for Hypercapnic COPD Patients NCT05829083NA2 sites๐Ÿ“ Athens๐Ÿ“ Larissa Larissa University Hospital ยท Tests: Asymmetric nasal cannula - DUET, Conventional nasal high flow cannula Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting NCT05012033n/a1 site๐Ÿ“ London Imperial College London ยท Tests: No intervention - prednisolone is taken as part if routine clinical care. Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation NCT07072039NA1 site๐Ÿ“ Worcester University of Massachusetts, Worcester ยท Tests: Paramedic Evaluation for acute COPD Exacerbation, Usual Care Effect of IMT in Patients After Acute Exacerbations of COPD NCT07213128NA12 sites๐Ÿ“ Aalst๐Ÿ“ Anderlecht๐Ÿ“ Brussels KU Leuven ยท Tests: Training Effectiveness of DITM Versus IMT in COPD Patients NCT06958666NA9 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou๐Ÿ“ Lishui Sir Run Run Shaw Hospital ยท Tests: Digital Inhaled Therapy Management, Inspiratory Muscle Training Predicting Acute Exacerbations of COPD Using Wearable Devices and Remote Monitoring Technology With AI/ML Models NCT06802003n/a1 site๐Ÿ“ Montreal McGill University Health Centre/Research Institute of the Mโ€ฆ ยท Tests: Biometric wearable and handheld devices Home High Flow Oxygen to Reduce Acute Exacerbation of COPD NCT05196698NA1 site๐Ÿ“ Rouen University Hospital, Rouen ยท Tests: High Flow Oxygen Therapy, Long-term oxygen therapy Use of MULTIplex PCR, Procalcitonin, and Sputum Appearance to Reduce Duration of Antibiotic Therapy During Severe COPD EXAcerbation: A Controlled, Randomized, Open-label, Parallel-Group, Multicenter Trial NCT05280132NA1 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris ยท Tests: Personalized antibiotic treatment, Usual antibiotic treatment COPD-ICU Multicentre Prospective Observational Register NCT05734365n/a1 site๐Ÿ“ Le Chesnay Versailles Hospital
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