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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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29 recruiting trials

for Focal Drug-resistant Epilepsy

Temporal Interference Brain Stimulation for Adults With Drug-Resistant Epilepsy Undergoing Stereo-EEG Monitoring NCT07764718NA1 site📍 Durham Duke University · Tests: Temporal Interference Stimulation, Direct Electrical Stimulation Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain NCT03268824n/a1 site📍 Paris Fondation Ophtalmologique Adolphe de Rothschild · Tests: Electroencephalogram (EEG), Diffusion Tensor imaging, Language assessment Focused Ultrasound for Drug-resistant Epilepsy NCT06292494NA1 site📍 Taipei Taipei Veterans General Hospital, Taiwan · Tests: Exablate 4000 Transcranial MRgfUS System Spatial Scene Recognition Memory in Epilepsy Surgery NCT07580183NA2 sites📍 Sacramento📍 Atlanta University of California, Davis · Tests: Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimag… The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy NCT07095933EARLY Phase 11 site📍 Beijing Xuanwu Hospital, Beijing · Tests: Everolimus Study for the Diagnosis and Treatment of Drug-resistant Focal Epilepsies NCT06794606n/a1 site📍 Milan Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy NCT05518578Phase 210 sites📍 Jacksonville📍 Miami📍 Randwick Supernus Pharmaceuticals, Inc. · Tests: SPN-817 Exploring the Characteristics of Epileptogenic Foci in Drug-Resistant Epilepsy Based on Multimodal Imaging Technology NCT06557720n/a1 site📍 Xi'an Xijing Hospital Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy)) NCT05135091Phase 335 sites📍 Birmingham📍 Phoenix📍 Tucson Neurona Therapeutics · Tests: NRTX-1001, NRTX-1001, Sham Comparator Electroclinical Correlation of Anxiety NCT05393518NA1 site📍 Bordeaux University Hospital, Bordeaux · Tests: Anxiety-induced task, Neuropsychiatric assessment A PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome NCT07013331NA1 site📍 Bron Hospices Civils de Lyon · Tests: [18F]MPPF PET-MRI Sirolomus Adjuvant Treatment of Focal Refractory Epilepsy (SATFRE) NCT06719791EARLY Phase 11 site📍 Beijing Xuanwu Hospital, Beijing · Tests: Sirolimus Impact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory Reactivity NCT07249034NA1 site📍 Bron Hospices Civils de Lyon · Tests: 1 Hypercapnic challenge while participant is awake, PET/MRI acquisition A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy NCT06388707Phase 1, Phase 23 sites📍 Palo Alto📍 Boston📍 Charlottesville NaviFUS Corporation · Tests: NaviFUS System Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables NCT07012148EARLY Phase 13 sites📍 Scottsdale📍 Jacksonville📍 Rochester Mayo Clinic · Tests: UNEEG SubQ device, seizure forecasts, nasal diazepam, Preventative Medication (PM) Subthalamic Nucleus Electrical Stimulation for Drug-resistant Focal Motor Epilepsy NCT06248333NA1 site📍 Beijing Xuanwu Hospital, Beijing · Tests: STN-DBS ON, STN-DBS OFF Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies NCT02890641n/a1 site📍 Paris Fondation Ophtalmologique Adolphe de Rothschild · Tests: Sampling of blood, frozen resected tissues, and cerebrospinal fluid (CSF) Atlas of Human Cognition by SEEG (MAPCOG-SEEG) NCT03644732n/a4 sites📍 Grenoble📍 Nancy📍 Paris University Hospital, Grenoble · Tests: SEEG Group Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy NCT06210022n/a1 site📍 Milan IRCCS San Raffaele · Tests: Neuropsychological Assessment Links Between Epileptic Activity, Sleep Disruption and Mental Content During Sleep NCT07605858n/a2 sites📍 Durham📍 Bron Hospices Civils de Lyon · Tests: Direct Electric Stimulation (DES) Multimodal Study of the Human Brain Epilepsy Tissue NCT06022055NA1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Blood and tissue collection Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial NCT03868293NA1 site📍 Boston Brigham and Women's Hospital · Tests: Focused ultrasound Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy NCT07680842NA1 site📍 San Francisco University of California, San Francisco · Tests: Target optimization using LIFU, Serial LIFU stimulation A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy NCT06492720NA1 site📍 Taipei NaviFUS Corporation · Tests: Focused ultrasound (FUS) treatment Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy NCT02531880Phase 11 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: Mangafodipir, Gadolinium Biomarkers of Response to SEEG Thermocoagulation NCT07399327NA1 site📍 Marseille Assistance Publique Hopitaux De Marseille · Tests: Quality of life questionnaires (QOLIE, EFIQUACEE for children), psychiatric questionnaires (NDDIE, GAD-7, PCL-5) at Vis… Evaluation of the NaviFUS System in Drug Resistant Epilepsy NCT05947656NA1 site📍 Melbourne Genovate-NaviFUS (Australia) Pty Ltd. · Tests: NaviFUS System National Registry of Rare Kidney Diseases NCT06065852n/a1 site📍 Bristol UK Kidney Association Localizing Epileptic Networks Using MRI and iEEG NCT04649008EARLY Phase 11 site📍 Philadelphia University of Pennsylvania · Tests: 3T Magnetic Resonance Imaging, Intracranial electroencephalography recordings, 7T Magnetic Resonance Imaging
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