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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Genetic Eye Disease

An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene NCT06435000n/a20 sites๐Ÿ“ San Diego๐Ÿ“ Aurora๐Ÿ“ Gainesville Splice Bio Neurodegenerative Diseases Progression Markers (MARKERS-NDD) NCT06596746n/a1 site๐Ÿ“ Cassino Casa di Cura San Raffaele Cassino ยท Tests: Observation Diet Restiction in Subjects With Behcet Disease and Complaint of Tinnitus NCT07702149NA2 sites๐Ÿ“ Giza๐Ÿ“ Dokki Cairo University ยท Tests: diet restriction OCT in Fuchs' Dystrophy NCT04258787n/a1 site๐Ÿ“ Portland Oregon Health and Science University HYPER MIND - Hyperoxia Effects on Cerebral Hemodynamics NCT07377162NA1 site๐Ÿ“ Brussels Erasme University Hospital ยท Tests: Normobaric Hyperoxic Stimulus (NBHO) Clinical and Molecular Studies in Families With Inherited Eye Disease NCT02771236n/a10 sites๐Ÿ“ La Jolla๐Ÿ“ Bethesda๐Ÿ“ Durham National Eye Institute (NEI) A Natural History Study of Corneal Abrasions in Patients With Dystrophic Epidermolysis Bullosa (DEB) NCT06563414n/a1 site๐Ÿ“ Pittsburgh Krystal Biotech, Inc. Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions NCT02077894n/a1 site๐Ÿ“ Bethesda National Eye Institute (NEI) Modeling Ocular Developmental Diseases From 3D Cultures of Optic Vesicle Organoids Derived From hiPSCs of Patients With Ocular Malformations NCT06408701n/a2 sites๐Ÿ“ Clermont-Ferrand๐Ÿ“ Toulouse University Hospital, Toulouse ยท Tests: Blood sampling Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy NCT04440280Phase 21 site๐Ÿ“ Boston Massachusetts Eye and Ear Infirmary ยท Tests: N-acetyl cysteine (NAC) 10% solution, N-acetyl cysteine (NAC) 20% solution, Visine Dry Eye Relief eye drops Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH) NCT06445322n/a9 sites๐Ÿ“ San Francisco๐Ÿ“ Gainesville๐Ÿ“ Baltimore Ascidian Therapeutics, Inc ยท Tests: Prescreening Assessments The OPTIMISE Study NCT05716945Phase 48 sites๐Ÿ“ Apeldoorn๐Ÿ“ Nijmegen๐Ÿ“ Maastricht Maastricht University Medical Center ยท Tests: Fluorometholone 0.1% Oph Susp, Dexamethasone 0.1% ophthalmic suspension, Stop steroids Characterization and Contribution of Genome-wide DNA Methylation (DNA Methylation Episignatures) in Rare Diseases With Prenatal Onset NCT06475651n/a1 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris ยท Tests: Methylation analysis Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology NCT07136844NA1 site๐Ÿ“ Liรจge Centre Hospitalier Universitaire de Liege ยท Tests: Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT), The 10-meter test (10MWT), The 4 staโ€ฆ BS01 in Patients With Retinitis Pigmentosa NCT04278131Phase 1, Phase 21 site๐Ÿ“ Teaneck Bionic Sight LLC ยท Tests: BS01 Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy NCT01243931NA1 site๐Ÿ“ Portland Oregon Health and Science University ยท Tests: OCT-guided laser phototherapeutic keratectomy Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics NCT00001373n/a5 sites๐Ÿ“ Washington D.C.๐Ÿ“ Baltimore๐Ÿ“ Bethesda National Human Genome Research Institute (NHGRI) Precision Diagnosis and Therapy for Rare Diseases by Interpreting Non-coding Genomes NCT06775561n/a1 site๐Ÿ“ Bologna IRCCS Azienda Ospedaliero-Universitaria di Bologna ยท Tests: PARADIGM study aims to streamline the process from genomic characterization of RGD patients with ED/NMD to identificatiโ€ฆ A Study of GenSci098 in Subjects With Active Thyroid Eye Disease NCT06569758Phase 11 site๐Ÿ“ Shanghai Changchun GeneScience Pharmaceutical Co., Ltd. ยท Tests: GenSci098, GenSci098 Placebo Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal Dominant Optic Atrophy (Myrtle) NCT06970106Phase 1, Phase 23 sites๐Ÿ“ Sydney๐Ÿ“ East Melbourne๐Ÿ“ Auckland PYC Therapeutics ยท Tests: PYC-001 Screening, Classification, and Outcome Prediction Ensemble Using Orbital MRI for Thyroid Eye Disease: The TED SCOPE National Multicenter Registry Study NCT07716397n/a1 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: MRI scan๏ผŒocular ultrasound Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site๐Ÿ“ Pittsburgh Paul Szabolcs ยท Tests: data collection Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION) NCT06891443Phase 318 sites๐Ÿ“ San Francisco๐Ÿ“ Miami๐Ÿ“ Iowa City Laboratoires Thea ยท Tests: sepofarsen, Placebo IVT BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases NCT06794008Phase 21 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: BCMA-CD19 CAR-T therapy Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION NCT05147701Phase 12 sites๐Ÿ“ Naples๐Ÿ“ Athens The Foundation for Orthopaedics and Regenerative Medicine ยท Tests: cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes A Longitudinal Natural History Study of OPA1-Associated Autosomal-Dominant Optic Atrophy NCT07729982n/a1 site๐Ÿ“ Munich Ludwig-Maximilians - University of Munich Progression Assessment of PXE-associated Alterations NCT07048106n/a1 site๐Ÿ“ Bonn University Hospital, Bonn A Study of Teprotumumab N01 in Subjects With Active Thyroid Eye Disease NCT07265258Phase 41 site๐Ÿ“ Shanghai Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: Teprotumumab N01, Methylprednisolone A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa NCT06628947Phase 25 sites๐Ÿ“ Sydney๐Ÿ“ Woolloongabba๐Ÿ“ Adelaide Kiora Pharmaceuticals, Inc. ยท Tests: Placebo (Sterile Saline or Balanced Salt Solution), 100 ฮผg KIO-301, 50 ฮผg KIO-301 Hydroxychloroquine in Mild Graves' Orbitopathy NCT05126147Phase 42 sites๐Ÿ“ Hsinchu๐Ÿ“ Taipei National Taiwan University Hospital ยท Tests: Hydroxychloroquine
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