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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Nicotine Use Disorder

Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users NCT07886099NA1 site๐Ÿ“ Bangkok Chulalongkorn University ยท Tests: Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition Overcoming Nicotine Dependence to Enable Quitting NCT05513872Phase 1, Phase 21 site๐Ÿ“ Chicago Rush University Medical Center ยท Tests: Nicotine Replacement Therapy (NRT) Sampling, Practice Quitting (PQ) Counseling, Motivational Interviewing (MI) Counseliโ€ฆ Young Adult Tobacco/Nicotine and Cannabis Co-use NCT06239350NA1 site๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: Counseling, Contingency management, Text-based support MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education NCT06553196NA1 site๐Ÿ“ Northridge California State University, Northridge ยท Tests: MATAspire Web-app Behavioral Intervention for Youth to Promote Vaping Cessation NCT06765291NA1 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: QuitVaping, This is Quitting (TIQ) A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation NCT07487818Phase 2, Phase 31 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Non-invasive vagus nerve stimulator plus nicotine replacement patches, nicotine replacement patches Effects of Novel E-cigarette Constituents on Adults TCORS 3.0 NCT05932745NA1 site๐Ÿ“ New Haven Yale University ยท Tests: E-liquid coolant (No WS-3) for non-menthol (1), E-liquid coolant (No WS-3) for low (0.1%) menthol (1), E-liquid coolantโ€ฆ Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking NCT05665465EARLY Phase 11 site๐Ÿ“ Durham Duke University ยท Tests: Nicotine nasal spray 0.5 mg, Placebo Circuitry-Guided Smoking Cessation in Schizophrenia (UH3) NCT05276050NA1 site๐Ÿ“ Houston The University of Texas Health Science Center, Houston ยท Tests: active F8-coil delivered rTMS, active H-coil delivered rTMS Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke NCT06654414NA3 sites๐Ÿ“ Boston๐Ÿ“ Boston๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: PRIDE QUIT, Enhanced Treatment As Usual (ETAU) Implementation of Transcranial Magnetic Stimulation for Smoking Cessation NCT06346028Phase 41 site๐Ÿ“ Toronto Centre for Addiction and Mental Health ยท Tests: Brainsway H4 deep rTMS coil and Brainsway stimulator system The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction NCT07322432Phase 21 site๐Ÿ“ New York VapeAway ยท Tests: VapeAway filter system Effects of Cannabidiol on Stress and Nicotine Withdrawal NCT07001930Phase 11 site๐Ÿ“ Baltimore Johns Hopkins University ยท Tests: Epidiolex Semaglutide for Smoking Cessation in Patients With Diabetes NCT07059377Phase 31 site๐Ÿ“ Ottawa Ottawa Heart Institute Research Corporation ยท Tests: Semaglutide, Nicotine replacement Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging NCT01036581NA1 site๐Ÿ“ Baltimore National Institute on Drug Abuse (NIDA) ยท Tests: MagPro X100 Magnetic Stimulator, Transcranial Rotating Magnetic Stimulator, Magnetom Prisma Fit 3T Scanner Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study) NCT07145866Phase 41 site๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham, Nicotine Cessation Counseling, โ€ฆ Opioids, Low Nicotine Cigarettes, and Chronic Pain NCT06747871NA1 site๐Ÿ“ Durham Duke University ยท Tests: Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC) Abuse Liability and Appeal of Oral Nicotine Products NCT06506162NA2 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles University of Southern California ยท Tests: Flavor, Nicotine concentration Non-Invasive Deep Brain Neuromodulation for Smoking Cessation NCT07298902NA1 site๐Ÿ“ Houston The University of Texas Health Science Center, Houston ยท Tests: Low intensity focused ultrasound with active stimulations, low intensity focused ultrasound with sham stimulations Identify the Optimal TMS Target to Modulate Reward Activity NCT05766254NA1 site๐Ÿ“ Newark Rutgers, The State University of New Jersey ยท Tests: Active 10-Hz TMS to the DLPFC, Sham TMS-DLPFC Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial NCT06534047Phase 41 site๐Ÿ“ Toronto Centre for Addiction and Mental Health ยท Tests: Brainsway H4 deep Repetitive Transcranial Magnetic Stimulation (rTMS) coil, Nicotine replacement Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking NCT05181891Phase 21 site๐Ÿ“ Spokane Washington State University ยท Tests: Contingency Management, Non-contingent control Neuroimaging Approaches to Improve Prediction of Smoking Initiation and Nicotine Escalation in Young Adult ENDS Users NCT05447325NA1 site๐Ÿ“ Athens University of Georgia ยท Tests: Exposure to Anti-Vaping Messages (generic themes then flavor-specific themes), Exposure to Anti-Vaping Messages (flavorโ€ฆ Smoking Cessation and Menstrual Cycle Phase NCT05515354Phase 41 site๐Ÿ“ Toronto Centre for Addiction and Mental Health ยท Tests: Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent Sex Differences in E-Cigarette Perception NCT07398976NA1 site๐Ÿ“ New Haven Yale University ยท Tests: Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml) Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine NCT05962229Phase 11 site๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: (S)-Nicotine, (R)- nicotine, Racemic nicotine E-cigarette Cessation in Adults Who Co-use Cannabis NCT06688539Phase 43 sites๐Ÿ“ Charleston๐Ÿ“ Lancaster๐Ÿ“ Pickens Medical University of South Carolina ยท Tests: Varenicline Pill, Contingency management, Counseling A Trial of Varenicline for E-cigarette Cessation NCT07040566Phase 22 sites๐Ÿ“ New Haven๐Ÿ“ Charleston Yale University ยท Tests: Varenicline 1mg BID, Placebo Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches NCT06678789NA1 site๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: High Nicotine Dose, Low Nicotine Dose Use of Nicotine Pouches Among Daily Smokers NCT06043362NA2 sites๐Ÿ“ Hershey๐Ÿ“ Houston Milton S. Hershey Medical Center ยท Tests: 0 mg nicotine pouch, 3 mg nicotine pouch, 6 mg nicotine pouch, Smooth nicotine pouch, Wintergreen nicotine pouch
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